Objective: To observe the effect on diabetic peripheral neuropathy of DL-thioctic acid combined with the Chinese medicine foot massage under the guidance of dynamics-immobility-order-succession and eight methods therapy. Method: Seventy patients were enrolled according to the inclusion and exclusion criteria in this study. Then the patients were randomly divided into the control group and the observation group. The patients in both groups received basis treatment and patients in observation group received Chinese medical foot massage for two two-weeks courses. Scores of Chinese medical symptom

neural symptoms and signs were graded before and after treatment. The ankle-brachial index (ABI) in lower extremity arterial blood flow

common peroneal nerve conduction velocity including motor conduction velocity (MCV) and sensory conduction velocity (SCV) were evaluated before and after treatment. The adverse reactions of treatment were carefully monitored in this study. Result: Scores of Chinese medical symptom

neural symptoms and signs in observation group were lower than that in control group after treatment (P<0.05). Scores of ABI

MCV and SCV were significantly higher in observation group as compard with that in control group (P<0.05). No serious adverse reactions were found. Conclusion: DL-thioctic acid combined with Chinese medicine foot massage under the guidance of dynamics-immobility-order-succession and eight methods therapy can improve the clinical symptoms and the lower extremity arterial blood flow in patients with diabetic peripheral neuropathy

which provide a new method for treatment of diabetic peripheral neuropathy using Chinese medicine.