53味清热类中药对绿脓杆菌抑菌作用的聚类分析

何先元; 李坤; 喻录容; 刘俊康; 廖巳祥; 刘艳霞

doi:10.13422/j.cnki.syfjx.2014200222

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53味清热类中药对绿脓杆菌抑菌作用的聚类分析

数据挖掘 | 更新时间：2024-01-04

- 53味清热类中药对绿脓杆菌抑菌作用的聚类分析
- Cluster Analysis of 53 Chinese Antipyretic Herbs on Bacteriostatic Effects Against Pseudomonas Aeruginosa
- 中国实验方剂学杂志 2014年20卷第20期页码：222-225
- 作者机构：
- 作者简介：
- 基金信息：
  
  重庆市卫生局科技项目（2012-2-144）
- DOI：10.13422/j.cnki.syfjx.2014200222
  中图分类号： R446.5
- 纸质出版日期：2014
- 稿件说明：
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何先元, 李坤, 喻录容, 等. 53味清热类中药对绿脓杆菌抑菌作用的聚类分析[J]. 中国实验方剂学杂志, 2014,20(20):222-225.

HE Xian-yuan, LI Kun, YU Lu-rong, et al. Cluster Analysis of 53 Chinese Antipyretic Herbs on Bacteriostatic Effects Against Pseudomonas Aeruginosa[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(20): 222-225.
何先元, 李坤, 喻录容, 等. 53味清热类中药对绿脓杆菌抑菌作用的聚类分析[J]. 中国实验方剂学杂志, 2014,20(20):222-225. DOI： 10.13422/j.cnki.syfjx.2014200222.

HE Xian-yuan, LI Kun, YU Lu-rong, et al. Cluster Analysis of 53 Chinese Antipyretic Herbs on Bacteriostatic Effects Against Pseudomonas Aeruginosa[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(20): 222-225. DOI： 10.13422/j.cnki.syfjx.2014200222.

摘要

目的：通过对53味清热类中药对绿脓杆菌的抑菌作用的聚类分析，了解它们抑菌效果的差异，指导临床用药。方法：通过药敏纸片法测定抑菌环直径和液体培养测定吸光度（A）确定中药的抑菌效果。结果：聚类分析表明清热中药抑制绿脓杆菌效果的类群与传统分类存在不一致现象。结论：临床上对于防治绿脓杆菌的感染，可选用赤芍、胡黄连、黄连、蒲公英、丝瓜络、黄芩、密蒙花等清热类中药。

Abstract

Objective: The bacteriostatic effects of 53 Chinese antipyretic herbs against pseudomonas aeruginosa and their antibacterial difference were classified and confirmed by cluster analysis in order to instruct clinical administration. Method: Antibacterial effect of traditional Chinese medicine was ascertained by determination of diameter of inhibition zone K-band in liquid culture. Result: The cluster analysis showed that the classification of bacteriostatic Pseudomonas aeruginosa effects were not consistent with traditional classification of Chinese antipyretic herbs group. Conclusion: For the clinical prevention of P. aeruginosa infection

the optional Chinese antipyretic herbs were suggested as paeoniae radix rubra

picrorhizae rhizoma

coptidis rhizoma

taraxaci herba

luffae fructus retinervus

scutellariae radix

buddlejae flos

etc.

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