Objective:A randomized

double-blind

parallel-group

multi-center prospective clinical trial was conducted to the superiority and efficacy study of Yitangkang in treating patients with metabolic syndrome. Method: One hundred and sixty-five patients with metabolic syndrome were randomly divided into the observation group and the control group. The western medicinal targets (glucose

glycosylated hemoglobin

body mass index)

and traditional Chinese medicinal (TCM) indicators (TCM patterns indicators

TCM syndrome indicators

quality of life score

etc.) were compared between groups before and after treatment. Result: ①Yitangkang can improve fasting glucose

2-hour postprandial blood glucose

blood pressure and body mass index of patients. ②Yitangkang can increase the compliance rate of fasting glucose

2-hour postprandial glucose and body mass index. ③Yitangkang can effectively improve the clinical symptoms and systemic conditions

and improve the quality of life in patients with metabolic syndrome. Conclusion: ①Yitangkang can reduce the clinical risk factors by decreasing the blood glucose and weight of patients with metabolic syndrome. ② Chinese medicine treatment can delay the progression of the metabolic syndrome and improve the quality of life of patients

which are worthy widely applied.