Objective: To investigate the clinical effect of Liqi Qingre Fang by jejunal injection in combination with conventional symptomatic and supportive intervention in treating acute pancreatitis (AP). Method: Eighty patients with AP accorded with the inclusion criteria were randomly divided into two groups of 40 patients each. The patients in both groups received conventional symptomatic and supportive intervention and the patients in observation group added Liqi Qingre Fang by jejunal injection. The curative efficacy

relevant clinical indices and inflammatory factors were observed and compared. Result: The patients in observation group had a total therapeutic ratio of 92.5%

which was statistically higher than that of 70.0% in the control group (P<0.05). The disappearance time of abdominal pain

vomiting

fever

jaundice and the recovery time of serum amylase in the observation group were shorter than those in control group (P<0.05). After the treatment

inflammatory factors of interleukins (IL) -6

IL-8

tumor necrosis factor alpha(TNF-α) and high-sensitivity C-reactive protein(Hs-CRP) in the observation group were statistically lower than those in the control group (P<0.05). Conclusion: The effect of using Liqi Qingre Fang by jejunal injection in combination with conventional symptomatic and supportive intervention is reliable in treating AP. It could increase the toal therapeutic ratio

improve relevant indices and alleviate inflammatory reaction

which is worthy to be applied widely in clinic.