Objective: To study on re-evaluation of extraction process of Qingnao Fushen liquids

to provide experimental basis for improving industrial production of this preparation. Method: Determination of baicalin by HPLC

mobile phase of methanol-0.37% phosphoric acid(47:53)

detection wavelength of 280 nm.Taking composite score of amounts of dry extract and baicalin as indexes

orthogonal test was adopted to optimize percolation process with the amount of solvent

percolation velocity

ethanol concentration as factors.Physical and chemical properties of different extracts were compared through ultraviolet scanning

near infrared scanning and infrared scanning. Result: Optimum extraction condition was as following:percolated by 8 times the amount of 40% ethanol at 2.27 mL·min-1·kg-1;amounts of dry extract and baicalin were 21.64 g and 31.23 mg.Ultraviolet full wavelength scanning

near infrared scanning

infrared scanning and dry extract amount of percolate and immersion fluid were most the same. Conclusion: Effective ingredients extracted from these two kinds of extraction process are all most the same

so percolation process can substitute immersion method.