Objective: Developing a method for detecting benzene series residues from HPD-300 macroporous resin for Chuanxiong Rhizoma extract

to provide a reference for promotion of macroporous resin. Method: Chuanxiong Rhizoma extract was dissolved by dimethyl sulfoxide

headspace sampling method was adopted

residues of organic solvent in macroporous resin was determined by capillary gas chromatography

column was temperature-programmed(initially heated at 50℃ for 10 min;rose to 70℃ with a speed of 5℃·min-1

1asting for 16 min;then rose to 120℃ with a speed of 5℃·min-1

1asting for 10 min)

inlet temperature was 220℃

split ratio was 10:1

pressure was 58.799 kPa

total flow was 10.772 mL·min-1

H2 flow was 40 mL·min-1

air flow was 300 mL·min-1

make-up(N2) flow was 30 mL·min-1

carrier gas(N2) flow was 20 mL·min-1.Headspace conditions were:sample temperature at 80℃

manifold temperature at 100℃

pipe temperature at 110℃

balance time of 30 min

sampling interval of 55 min and sample quantity of 1 mL. Result: Linear relations between peak area and mass concentration of seven residues were good with r>0.999

average recoveries of n-hexane

cyclohexane

benzene

toluene

xylene

styrene

divinyl-benzene were 99.2%

97.3%

103.4%

98.7%

97.0%

101.9% and 98.5%

respectively. Conclusion: This method can be used for detecting benzene series residues in HPD-300 macroporous resin.