Objective: To optimize extraction technology of rheumatism ostalgia alcohols and establish its quality standard. Method: HPLC was adopted to determine the content of curcumin with mobile phase consisting of 4% glacial acetic acid-acetonitrile(52:48) and detection wavelength at 430 nm.With composite score of amounts of general solid and curcumin as index

orthogonal design was employed to optimize extraction technology of rheumatism ostalgia alcohols with soaking time

ethanol concentration and amount as factors.Angelicae Sinensis Radix

Ventilago Leiocarpae Radix et Caulis

Curcumae Longae Rhizoma and Acanthopanacis Cortex were identified by TLC. Result: Curcumin showed a good linear relationship at a range of 0.021 2-0.106 μg with r of 0.999 8 and average recovery of 97.81%.Optimal extracting technology was:soaked 30 days with 10 times the amount of 50% ethanol.TLC spots were clear and the blank test showed no interference. Conclusion: This technology is stable feasible with high extraction amount of index ingredient

which is available for industrial production of rheumatism ostalgia alcohols.This established TLC can control quality of this preparation effectively.