WANG Mei-na, LI Yuan-xin, CAI Xing. Performances and Applications Overview of Carboxythmethyl Chitosan[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(1): 228-232.
WANG Mei-na, LI Yuan-xin, CAI Xing. Performances and Applications Overview of Carboxythmethyl Chitosan[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(1): 228-232. DOI: 10.13422/j.cnki.syfjx.2015010228.
hemostatic effect are well.Carboxymethyl chitosan calcium has a certain antioxidant capacity and liver protection for acute liver injury mice induced by CCl4.Based on these above investigation
application prospect of carboxymethyl chitosan in medicine
food
cosmetics and other fields is described.It can be used in vivo and in vitro as medical materials;it has many characteristics as drug carriers
such as water solubility
biocompatibility and so on
so it can extend residence time of drug in specific parts
then improve bioavailability;it can be used as an sunscreen for cosmetics with excellent UV absorption features and safety;after combined with other materials
it can promote growth of fibroblast as a new injectable soft tissue filler material with good biocompatibility;it also can be used as adsorbent
flocculant and separation membrane material for purification of drinking water
recycling of heavy metal ions
et al.Carboxymethyl chitosan has viscosity
which can extend residence time of drug in the nasal cavity and increase contact time of drug and the nasal mucosa
then it improves bioavailability of drug through the nasal cavity
also plays long-lasting effect as sustained and controlled release preparations.