Objective: To observe the influence of Fuzheng Shugan decoction combined group psychotherapy in treating patients with stomach cancer after therapy. Method: Eighty patients were randomly divided into control group (40 cases) and observation group (40 cases) by random number table. Patients in control group received 20 mg fluoxetine capsules and 10-20 mg escitalopram citalopram tablets once daily. Patients in observation group received Fuzheng Shugan decoction combined group psychotherapy. Patients in both groups received 8 weeks of treatment. The self-rating anxiety scale (SAS)

self-rating depression scale (SDS)

Hamilton's depression scale (HAMD)

Herth hopes list (HHI) and cartesian function scale (KPS) were scored before and after treatment. The quality of life was evaluated using QLQ-STO22 questionnaire of European organization for research and treatment of cancer (EORTC) once before and after treatment. Result: The amelioration of quality of life in observation group was superior to that in control group after treatment (P<0.05)

while there was no statistic significance difference for antidepressant action between two groups. Scores of SAS and SDS in observation group were lower than those in control group (P<0.01)

while there was no statistic significance difference for the score of HAMD in two groups. Score of KPS was decreased in control group

while it was increased and the result was higher in observation group (P<0.01). Scores of dysphagia

stomachache

reflux hiccup

constrained diet

anxiety

dry mouth and taste from QLQ-STO22 in observation group were lower than those in control group (P<0.01). Scores of the total average of hope

positive attitude to present and future and taking positive action and keeping healthy relationships with others from HHI in observation group were higher than those in control group (P<0.01). Conclusion: Fuzheng Shugan decoction combined group psychotherapy treatment has a comparative effect as compared with fluoxetine capsules in treating depression of stomach cancer after therapy. It can improve the hope of life

stabilize and improve the quality of life and realize the higher-quality life of patients.