With rapid development of economy

market competition of topical pharmaceutical preparation is becoming increasingly fierce

the focus of market competition of price and quantity has been gradually replaced by brand and product quality

many pharmaceutical production enterprises have gradually improved their product quality management to a new level

which becomes strategic direction of enterprise development.With regard to all-round improvement of production quality management level of modern production enterprise of topical pharmaceutical preparation

it is significant to a great extent that production enterprise improves awareness of GMP of their production operation staffs.The 2010 edition of good manufacturing practices(GMP) covers analysis both in terms of software and hardware

such as production areas and equipments modification

staffing and technical documentation

in order to improve the overall management so that high level GMP implementation of pharmaceutical production can be ensured.Taking topical preparation as research object

through a lot of data research and literature collection

focused on the creams as an example

in view of current market demand of pharmaceutical preparation for external use

it should apply modern product quality management model with scientific methods to all-round improve production and quality of topical pharmaceutical preparation and to cut losses caused by product quality problem

so that enterprises could enhance their competitiveness and to better cope with market competition.