Objective: To optimize spray drying process of Stigma Maydis water extract and provide theory support for preparation of Stigma Maydis dispensing granules. Method: According to single factor tests

with composite score of contents of total flavonoids and total polysaccharides

moisture content

flour yield as index

influence of inlet air temperature

air flow and feed rate on spray drying process of Stigma Maydis water extract was investigated by orthogonal test.Contents of total flavonoids and total polysaccharides were determined by UV

detection wavelengths were 400 nm and 490 nm

respectively. Result: Optimum spray drying process was as follows:inlet air temperature of 180 ℃

air flow rate of 800 L · h-1

inlet rate of 20%.Contents of total flavonoids and total polysaccharides

moisture content

flour yield were 0.14%

2.71%

5.81% and 91.33%. Conclusion: This optimized process is rational and stable

it can provide experimental basis for industrial production and product development of Stigma Maydis dispensing granules.