Objective: To observe the clinical effect of Shixiang plaster on treating chronic ulcer by randomized multicenter research. Method: One hundred and fifty-five patients with chronic ulcer from multicenter were randomly divided into the experimental group and the control group. Eighty patients in the experimental group were treated with Shixiang plaster

and the others in the control group were treated with Kangfuxin liquid. The wound healing rate

healing time

and visual analogue scale were recorded. Result: The wound healing rate showed statistical differences between two groups after 14 days treatment. There were no statistical differences in visual analogue scale between the two groups before treatment

while the visual analogue scale decreased more in the experimental group after treatment than the control group. The healing time in

the experimental group were much lower than the control group. The total curative effect in the experimental group was better than the control group. Conclusion: Shixiang plaster could improve the healing of the wound

which is worthy of clinical promotion.