Objective: To establish GC fingerprints of volatile oil from Chuanxiong Rhizoma. To compare the consistency of fingerprints of volatile oil from Chuanxiong Rhizoma by distillation coupling solvent extraction and traditional distillation extraction. Method: The volatile oil was extracted from Chuanxiong Rhizoma by distillation coupling solvent extraction.The chromatography fingerprints was established by AT-5 fused-silica capillary (0.32 mm×30 m

0.25 μm)column

injector temperature of 250 ℃

FID detector with temperature at 250 ℃.The similarity was calculated with "TCM fingerprint aided similarity evaluation software". Result: Established GC fingerprints of volatile oil from Chuanxiong Rhizoma.The reproducibility

accuracy and stability of the method were very good in the tests (all RSD<3%).The common components of volatile oil from Ligusticum chuanxiong by distillation coupling solvent extraction and traditional distillation extraction>98%.The similarity of common components was more than 0.998. Conclusion: The ligustilide from Chuanxiong Rhizoma by distillation coupling solvent extraction is 83.46 percent higher than traditional distillation extraction.The fingerprints of volatile oil from Chuanxiong Rhizoma by distillation coupling solvent extraction and traditional distillation extraction is consistent.