Objective: The aim of this study was to investigate the clinical effect of Jiannao Bushen pill combined with nimodipine on cognitive function and hemorheology index in elderly patients with vascular dementia (VD) and provide clinical basis for VD therapy. Method: From 2009/1 to 2013/1

we collected 90 VD cases in our hospital and divided them into 2 groups randomly

45 cases in control group and 45 cases in observation group. The control group was treated with conventional treatment and nimodipine

while the observation group was treated with conventional therapy

and Jiannao Bushen pill combined with nimodipine. Clinical effects

the mini mental state examination(MMSE) score

hemorheology index

and the levels of inflammatory factors were observed and compared. Result: The observation group had a therapeutic efficiency ratio (TER) of 95.6.0% which was significantly higher than the control group (77.8%)(P<0.05). The MMSE score

hemorheology index

and the levels of inflammatory factors of the both groups all significantly improved after treatments. However

those of the observation group were better improved than those of the control group after treatments (P<0.05). Conclusion: Jiannao Bushen pill combined with nimodipine for VD therapy is effective

which is worthy of study and further application in clinical treatment. Our study provided new evidence for clinical therapy of VD.