两面针商品药材的质量评价

张振山; 严萍; 谭志滨; 林文华; 童家赟; 詹若挺

doi:10.13422/j.cnki.syfjx.2015060057

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两面针商品药材的质量评价

化学与分析 | 更新时间：2024-01-04

- 两面针商品药材的质量评价
- Quality Evaluation of Medicinal Material of Zanthoxyli Radix
- 中国实验方剂学杂志 2015年21卷第6期页码：57-61
- 作者机构：
- 作者简介：
- 基金信息：
  
  中央财政支持地方高校发展专项资金项目-中药学(粤财教[2013]389号);广东省科技计划项目(2012A030100006)
- DOI：10.13422/j.cnki.syfjx.2015060057
  中图分类号： R284.1
- 纸质出版日期：2015
- 稿件说明：
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张振山, 严萍, 谭志滨, 等. 两面针商品药材的质量评价[J]. 中国实验方剂学杂志, 2015,21(6):57-61.

ZHANG Zhen-shan, YAN Ping, TAN Zhi-bin, et al. Quality Evaluation of Medicinal Material of Zanthoxyli Radix[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 57-61.
张振山, 严萍, 谭志滨, 等. 两面针商品药材的质量评价[J]. 中国实验方剂学杂志, 2015,21(6):57-61. DOI： 10.13422/j.cnki.syfjx.2015060057.

ZHANG Zhen-shan, YAN Ping, TAN Zhi-bin, et al. Quality Evaluation of Medicinal Material of Zanthoxyli Radix[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 57-61. DOI： 10.13422/j.cnki.syfjx.2015060057.

摘要

目的: 对市售两面针商品药材进行质量调查和评价。方法: 参照2010年版《中国药典》两面针项下方法

对18批两面针商品药材进行性状鉴别、薄层色谱及高效液相法检测氯化两面针碱含量

并建立两面针HPLC指纹图谱方法

结合相似度评价对样品药材进行鉴别分析。结果: 样品性状

薄层鉴别和含量测定的结果显示

9批药材有伪品掺杂现象;样品总灰分的含量是2.4%～6.4%

水分含量是7.0%～12.1%

醇溶性浸出物含量是2.2%～8.6%;HPLC测定中有2批样品检测不到氯化两面针碱

11批样品图谱与对照指纹图谱相似度低于0.8;18批药材均不符合2010年版《中国药典》标准。结论: 目前市场上的两面针药材品质参差不齐

伪品掺杂现象比较严重。

Abstract

Objective: To evaluate the quality of medicinal material of Zanthoxyli Radix in Chinese herbal medicine market. Method: The 18 batches of commercial medicinal material of Zanthoxyli Radix were identified and analysed by macroscopical identification

TLC

HPLC according to the Chinese Pharmacopoeia published in 2010.HPLC fingerprint was applied to evaluate the quality of Zanthoxyli Radix. Result: There were adulterants detected in 9 batches by the macroscopical identification

TLC and HPLC. The total ashes were between 2.4% and 6.4%

the moisture ranged from 7.0% to 12.1%

and the alcohol-soluble extract was in the range of 2.2% to 8.6%. Nitidine chloride was not be detected in 2 batches by HPLC. Compared to the HPLC fingerprint common mode of Zanthoxyli Radix

the similarity of 11 batches were less than 0.8. The 18 batches of samples were not complied with Chinese Pharmacopoeia in 2010. Conclusion: Currently

the quality of medicinal material of Zanthoxyli Radix in Chinese herbal medicine market varies greatly

and the phenomenon of adulterants doping is serious.

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