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纸质出版日期:2015
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周剑鹏, 夏虹. 腓股肌康复配合补肾益气活血方防治老年髋部骨折术后深静脉血栓形成[J]. 中国实验方剂学杂志, 2015,21(6):195-198.
ZHOU Jian-peng, XIA Hong. Bushen Yiqi Huoxue Fang in Combination with Massage on Prophylaxis of Deep Venous Thrombosis Following Postoperative Period of Aged Hip Arthroplasty[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 195-198.
周剑鹏, 夏虹. 腓股肌康复配合补肾益气活血方防治老年髋部骨折术后深静脉血栓形成[J]. 中国实验方剂学杂志, 2015,21(6):195-198. DOI: 10.13422/j.cnki.syfjx.2015060195.
ZHOU Jian-peng, XIA Hong. Bushen Yiqi Huoxue Fang in Combination with Massage on Prophylaxis of Deep Venous Thrombosis Following Postoperative Period of Aged Hip Arthroplasty[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 195-198. DOI: 10.13422/j.cnki.syfjx.2015060195.
目的: 观察补肾益气活血方与腓股肌康复预防老年髋关节置换术后深静脉血栓(DVT)形成的疗效。方法: 将符合标准的90例行髋关节置换术患者按随机分为3组各30例。中医组服用补肾益气活血方加腓股肌康复穴位按摩
肝素组皮下注射依诺肝素
对照组服用阿司匹林肠溶片。观察3组术前、术后第1
10天患肢周径和肿胀率的变化
血小板(PLT)
D-二聚体(D-D)
凝血酶原时间(PT)
部分凝血酶活化时间(aPTT)和下肢静脉彩超检查。结果: 中医组患者术后肢体肿胀消退率明显优于对照组和肝素组 (P < 0.01);PLT
D-D
PT
aPTT术后1 d 3组比较
差异无统计学意义
术后10 d中医组和对照组比较
差异呈显著性(P < 0.01)
中医组和肝素组比较
差异无显著性;中医组DVT 1例(3.33%)
肝素组DVT 1例(3.33%)
对照组DVT 6例(20.0%)
中医组术后DVT发生率明显低于对照组( P < 0.01)。结论: 补肾益气活血方与腓股肌康复预防老年髋关节置换术后DVT 发生的效果好
安全性高。
Objective: The aim of this paper was to observe the effectiveness of Bushen Yiqi Huoxue Fang in combination with massage on prophylaxis of deep venous thrombosis(DVT) following postoperative period of aged hip arthroplasty. Method: Ninety patients receiving surgery by the same group of doctors were randomly divided into traditional Chinese medicine (TCM) group
low-molecular-weight heparin(LMWH)group and control group
postoperative patients in TCM group were treated with Bushen Yiqi Huoxue Fang in combination with massage. In the LMWH group
30 patients were given LMWH after surgery;patiens in the control group took aspirin enteric-coated tablets. The limb circumference
routine blood test
blood coagulation function changes
hemodynamics of vessels by vascular ultrasound and the thrombosis were examined before surgery and one day
10 days after surgery
respectively. Result: In limb circumference variation
there was significant difference the three groups (P < 0.01). There was no significant difference of platelets
D-dimer (D-D)
prothrombin time(PT)
activeated partial thromboplastin time(aPTT) in all the three groups in the assay of one day after surgery
while significant difference (P < 0.01) appeared between the TCM group and the control group in the assay of 10 days after surgery. There was significant difference of the occurrence of DVT after surgery between the TCM group and the control group (P < 0.01).In TCM group
one DVT case (3.33%) was discovered. In LMWH group
one DVT case (3.33%) was discovered as well. While in the control group
6 DVT cases (20.0%) were found. Conclusion: On the basis of this study
it is more effective and safer to use Bushen Yiqi Huoxue Fang in combination with massage on prophylaxis of DVT following postoperative period of aged hip arthroplasty.
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