Objective: To establish determinations of soluble arsenic salt and insoluble arsenic salt in Huafeng Dan in order to provide a reference for quality control of this preparation. Method: Contents of As2S2 and As2O3 in 18 batches of Huafeng Dan were determined by titration and UV spectrophotometry

respectively. Result: This established determination of As2S2 was reproducible with average recovery of 97.61%.Linear range of As2O3 was 4-16 μg with average recovery of 98.42 %.In 18 batches of samples

mass fraction of As2S2was 0.012-0.021 3 g·g-1 with average value of 0.018 4 g·g-1

difference coefficien was 13.3%;mass fraction of As2O3 was 75.24-124.55 μg·g-1 with average value of 92.99 μg·g-1

difference coefficien was 15.3%. Conclusion: These determinations are simple and accurate

they can provide experimental basis for improvement of quality standards of Huafeng Dan.Contents of As2S2and As2O3 in different batches of samples are quite different.