Near infrared spectroscopy (NIR) is a rapid

nondestructive and green analytical technology

and its quantitative analysis technique is especially rapidly developing. Determination methods with small deviation and good repeatability designated byChinese Pharmacopoeia like HPLC

GC

CE

AAS and ICP-MS were used to obtain chemical reference. Then chemometrics models like PLS and ANN were established to predict the contents of chemical compositions in herbal medicines and compound Chinese medicinal preparation. The established models were commonly evaluated by indicators of correlation coefficient (R)

RMSEC (the root-mean-square error of calibration)

RMSEP (the root-mean-square error of prediction) and RMSECV (the root-mean-square error of cross-validation). NIR quantitative analysis technique of has broad research and application prospects in the content determination of effective compositions

index compositions

moisture

extract and volatile oil of herbal medicines and compound Chinese medicinal preparation

effective compositions of mineral medicines

optimization of preparation technologies

and real-time monitoring of pharmaceutical process.