Objective: To investigate the effect of Shenmai injection atomization inhalation on serum C- reactive protein(CRP)in patients with radiation pneumonitis effect changes and humoral immune function. Method: Fifty cases of radiation pneumonia were selected and randomly divided into experimental group and control group with 25 cases in each group. The experimental group in the same period of treatment on inhalationof Shenmai injection

the control group without drug. Each of the 50 patients before and after treatment the blood sampling time

concentration and determination of CRP and humoralimmune serum IgG

IgA

IgM

C3. According to the rating of acute radiation injury(RTOG) grading standard of radiation pneumonia 50 cases patients were graded. Result: CRP levels in two groups of patients showed varying degrees of decline

while the experimental group after inhalation of Shenmai injection of serum CRP decreased more significantly

the difference was statistically significant (P < 0.05). After the treatment

control group and experimental group serum CRP value by comparison has the remarkable difference (P<0.05). The acute radioactive lung injury classification stadard(RTOG) grading standards of radiation pneumonia will be gradedpatients

know the value of serum CRP and radioactive pneumonia was positively correlated with the severity of (r=0.72

P<0.05). Comparing the two groups before and after treatment in patients with the concentration of IgG

IgA

IgM

the difference was statistically significant(P<0.05)

the experimental group after the treatment

the concentration of complement C3 increased significantly in control group did not change significantly

the differences between these two groups by comparison with statistical significance (P<0.05). Conclusion: Inhalation of Shenmai injection can significantly reduce the clinical symptoms

reduce the inflammation reaction in patients with pneumonia level

improve body immune state of patients

enhance the immune function of organism.