Objective: To observe the clinical efficacy of Tangshang I decoction for oral administration combined Changchun Tangshang cream using externally in treating patients with second-degree burns. Method: Ninety patients were randomly divided into the control group (45 cases) and the observation group (45 cases) by a random number table. Patients in the control group received Changchun Tangshang cream externally. Patients in the observation group added Tangshang I decoction orally. Patients with superficial second-degree burns received 10 days of treatment

and patients with deep second degree burns received 28 days of treatment. Pain relief time

wound non-leakage time

wound healing time and heat toxin syndrome scores were recorded. Result: After therapy

pain relief time

wound non-leakage time

wound healing time of patients with superficial and deep second-degree burns in the observation group were shorter than those in the control group (P <0.01). The comprehensive curative effect in the observation group was superior to that in the control group (P <0.05). The heat toxin syndrome effect in the observation group was better than that in the control group (P <0.05). There was no statistically significant difference for anti-inflammatory effect between two groups. Conclusion: Tangshang I decoction combined Changchun Tangshang cream could promote burn wound healing

shorten the healing time

relieve the pain in patients with superficial and deep second-degree burns. It has definite comprehensive curative effect on burns and curative effect on heat toxin syndrome.