Objective: To investigate the clinical efficacy of Tongbi capsule combined with western medicine in the treatment of elderly patients with coronary heart disease and angina pectoris and guide the clinical application. Method: One hundred and eighty cases of angina patients were randomly divided into the study group and the control group with 90 cases in each. Control group received conventional western medicine treatment. Study group received Tongbi capsules 3 capsules each time

3 times daily based on the control group

8 weeks for 1 course. The clinical efficacies of two groups were compared. Result: There were 4 cases in study group and 3 cases in control group lost. The total efficiency in study group was 88.4%

significantly higher than that in control group (75.9%

P<0.05). Angina attack frequency

duration

angina pectoris integral

angina relief time after sublingual nitroglycerin

dosage of nitroglycerin in both groups decreased significantly while those in study group were significantly lower than that in control group. STsegment depression in lead number

T wave flattening the number of leads

T wave inversion number of leads in both groups decreased significantly while those in study group were significantly lower than that in control group. High sensitive C-reactive protein(Hs-CRP)

homocysteine junction(HCY)

interleukin-6(IL-6)

matrix metallopeptidase 9(MMP-9) and myeloperoxidase(MPO)in both groups decreased significantly while those in study group were significantly lower than that in control group. Conclusion: Tongbi capsule combined with conventional western medicine can significantly improve the clinical symptoms in patients with coronary heart disease and angina pectoris

reducing the pathogenesis of angina pectoris frequencies and shorten the onset time

improving the abnormal ECG

and has obviously antioxidant and anti-inflammatory effects

also with long-term clinical benefit good

we recommend it a reasonably use in clinical.