Objective: To prepare tannin lappaconitine compound

investigate its physicochemical properties and make an evaluation. Method: Tannin was used to deposit alkaloids for preparing tannin lappaconitine compound

which was identified by differential scanning calorimetry (DSC)

ultraviolet spectrum (UV) and Fourier transform infrared spectroscopy (FT-IR).The molar ratio between lappaconitine and tannin was determined by UV.The compound's sedimentation capacity in equal amount of proteins was determined in simulated artificial gastric juice

small intestine and colon fluid environments.On the basis of the compound's blood coagulation capacity

surface wound model was established to determine the compound's healing capability in Wistar rats. Result: Lappaconitine and tannin formed a new compound with the molar ratio of 1: 1.In simulated artificial gastric juice

small intestine and colon fluid environments

tannin lappaconitine compound's sedimentation capacity with equal amount of proteins were 0.63

0.46

0.92 mg

respectively.In terms of the wound healing capacity

the compound group was significantly higher than the control group and even superior to the positive tannin group. Conclusion: Lappaconitine and tannin form a type of new compound through the hydrogen bonding interaction.This compound can achieve blood coagulation effect through sedimentation of proteins in blood

and promote wound healing

hemostasis

anti-inflammatory analgesic effects by increasing its biological value.