Objective: To observe the effect of Duhuo Jisheng decoction in staging treatment to promote the fracture healing and relieve the osteoporosis of senile osteoporotic simple thoracolumbar compression fracture cases. Method: Totally 94 patients were randomly divided into the control group (46 cases) and the experiment group (48 cases) by treatment methods. The control group was treated by being injected with salcatonin intramuscularly every two days (50 U/time) and administered alendronate sodium enteric-coated tablets (10 mg/time

qd)

calcium carbonate and vitamin D3 tablets (1 tablet/day) and lying on hard bed

wearing lumbar replacer

taking lumbar exercises and other conservative western medicine therapies. Based on the therapies of the control group

the experiment group was also treated with Duhuo Jisheng decoction in staging treatment according to the fracture healing stage. Both groups were treated for four months. The vertebral compression and recovery were detected by X-ray film

and the anterior vertebral height

vertebral body angle and kyphotic Cobb angle were recorded. The pain of patients was evaluated by the pain visual analogue scale (VAS). The waist function was evaluated by Japanese orthopaedic association (JOA) score. The dual energy X ray absorptiometry was adopted to measure the bone density of the femoral neck. Result: The clinical efficacy in the experimental group was higher than that in the control group at the fourth month after the treatment according to Ridit analysis (P<0.05). The anterior vertebral height in the experimental group was higher than that in the control group (P<0.01). The vertebral body angle and kyphotic Cobb angle in the experimental group were less than that in the control group (P<0.01). The pain VAS score in the experimental group was inferior to the data in control group at the third and fourth months after the treatment (P<0.01). The pain VAS score in the experimental group declined more than that in the control group (P<0.01). The JOA score and femoral neck BMD in the experimental group were higher than that in the control group (P<0.01). Conclusion: Duhuojisheng decoction in staging treatment on senile osteoporotic simple thoracolumbar compression fracture can accelerate the fracture healing

reduce pain

waist function and enhance bone mineral density

with a superior clinical efficacy to conservative western medicine therapies.