Objective: To analyze the clinical application regularity of Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs. Method: The application of Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs in provincial grade 3 class A hospitals in recent three years (November 2009—November 2012) were retrieved

analyzed

summarized and concluded. Result: The order of herbs with the same clinical application frequency with Glycyrrhizae Radix et Rhizoma were as follows:Sargassum> vinegar-Kansui Radix> vinegar-Spurge> vinegar-Genkwa Flos

with Sargassum accounted for over 80%. As for the ratio

except for Sargassum that was consumed more than Glycyrrhizae Radix et Rhizoma (usually two to three times of the consumption of baked Glycyrrhizae Radix et Rhizoma)

all of vinegar-Kansui Radix

vinegar-Spurge and vinegar-Genkwa Flos were consumed less than Glycyrrhizae Radix et Rhizoma(mostly 1/10 of the consumption of baked Glycyrrhizae Radix et Rhizoma). Regarding comparable herbs with Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs

the top six comparable herbs with Glycyrrhizae Radix et Rhizoma group were Poria

Cinnamomi Ramulus

Paeoniae Radix Alba

Moutan Cortex

fired Persicae Semen

Ginseng Radix et Rhizoma Rubra tablets. Conclusion: In the Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs

the most frequent compatible herbs with Glycyrrhizae Radix et Rhizoma are Sargassum

which is followed by Kansui Radix and Spurge. It suggests that the application of 18 incompatible pairs in the same prescriptions is also an objective exist

instead of an absolute incompatibility. This study will provide certain significance in guiding the clinical application of Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs.