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纸质出版日期:2015
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李丽, 田丽娜, 任振兴, 等. 黄精多糖的结构分析及功能活性研究进展[J]. 中国实验方剂学杂志, 2015,21(15):231-234.
LI Li, TIAN Li-na, REN Zhen-xing, et al. Structural Analysis and Functional Activity Research Progress of Polygonatum Sibiricum Polysaccharides[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(15): 231-234.
李丽, 田丽娜, 任振兴, 等. 黄精多糖的结构分析及功能活性研究进展[J]. 中国实验方剂学杂志, 2015,21(15):231-234. DOI: 10.13422/j.cnki.syfjx.2015150231.
LI Li, TIAN Li-na, REN Zhen-xing, et al. Structural Analysis and Functional Activity Research Progress of Polygonatum Sibiricum Polysaccharides[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(15): 231-234. DOI: 10.13422/j.cnki.syfjx.2015150231.
黄精是一种传统的药食同源类中药
具有补气养阴、健脾、润肺、益肾等功能
主要含有多糖、甾体皂苷、蒽醌类化合物、生物碱、强心苷、木质素、维生素等化合物
而黄精多糖是黄精的主要活性成分。近年来
黄精多糖的组成结构分析及其功能活性的研究取得了很大的进展
本文通过查阅国内外相关文献
对黄精多糖的主要化学组成及其分子量测定、结构分析及功能活性进行系统的归纳
结果显示黄精多糖的化学组成主要有阿拉伯糖、半乳糖、葡萄糖、甘露糖、果糖和半乳糖醛酸
以及少量的木糖和葡萄糖醛酸;在药理活性方面
其具有一定的抗肿瘤、抗氧化与抗衰老、提高免疫力、调节血糖血脂、抗菌抗炎及调节细胞内分泌等作用
具有广泛的应用价值及市场前景。但是
缺少黄精多糖化学组成及其体内、体外生物学作用及机制的研究
因此
本文将对其应用前景进行讨论与展望
提出进一步的研究方向
为其保健品的开发及疾病的治疗提供理论依据。
Polygonatum sibiricum is a traditional Chinese medicine of drug Edible
with many functions of tonifying qi and nourishing yin
strengthening spleen and kidney
moistening lung and so on. It mainly contains polysaccharides
steroidal saponins
anthraquinones
alkaloids
cardiac glycosides
lignin
vitamins and other compounds
and polysaccharide is the main of them. In recent years
the study of composition structure analysis and functional activity of Polygonatum sibiricum polysaccharides (PSP )has made great progress. In this paper
the relevant research of the main chemical composition and molecular weight determination
the structure analysis and functional activity of PSP were systematically summarized by referring to retrieve related documents
the results showed the chemical composed of PSP mainly included arabinose
galactose
glucose
mannose
fructose and galacturonic acid
and small amounts of xylose and glucuronic acid
in terms of pharmacological activity
it has certain anti-tumor antioxidant and anti-aging
enhancing immunity
regulating blood glucose and lipid
anti-inflammatory and regulating cell endocrine effects
and broad application and market prospects. However
the lack of research about PSP chemical composition and biological effects and mechanisms in vivo or vitro
therefore
this article will discuss with the prospect of its application prospects and proposing further research
provide the theoretical basis of health care products and treatment of disease.
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