Objective: To discuss the efficacy of Bushen Tiaojing decoction in promoting ovulation among patients with polycystic ovarian syndrome (PCOS) and its effect on insulin resistance (IR) and serum leptin (LP). Method: Totally 114 patients were divided into the control group (57 cases) and the observation group (57 cases) by the random number table. Patients in the control group received ethinylestradiol and cyproterone acetate tablets and clomiphene citrate. Besides the therapy of the control group therapy

patients in the observation group were also given Bushen Tiaojing decoction. The treatment courses for both groups lasted for 3 menstrual cycles. The endometrial thickness

endometrium types (A

B

C)

cervical mucus scores

number of eggs ovulated

menstruation recovery

encyesis were observed. The insulin resistance index (HOMA-IR)

leptin (LP)

luteinizing hormone (LH)

serum testosterone (T)

estradiol (E2) and follicle stimulating hormone (FSH) were detected. Result: After the treatment

the endometrial thickness and cervical mucus scores in the observation group were higher than that in the control group (P <0.01). After the treatment

type A endometrium in the observation group was higher than that in the control group (P <0.05). The menstruation recovery

number of eggs ovulated

encyesis in the observation group were higher than that in the control group (P <0.05). T

LH

HOMA-IR and LP levels in the observation group were lower than that in the control group (P <0.01). Conclusion: Combined with the western therapies

Bushen Tiaojing decoction can improve endometrial thickness and endometrial morphology

promote menstruation recovery

induce ovulation and enhance encyesis. Its mechanism may be correlated with the regulation of endocrine and metabolism.