Effect of Salviae Miltiorrhizae Radix et Rhizoma Polyphenols Acid Salt Combined with Adenosine Cyclophosphate Meglumine on Hemorheology, hs-CRP and NT-proBNP of Post-PCI Patients With Coronary Heart Disease
CHENG Zhan-ran, CHEN Xiao-hu. Effect of Salviae Miltiorrhizae Radix et Rhizoma Polyphenols Acid Salt Combined with Adenosine Cyclophosphate Meglumine on Hemorheology, hs-CRP and NT-proBNP of Post-PCI Patients With Coronary Heart Disease[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(17): 152-155.
CHENG Zhan-ran, CHEN Xiao-hu. Effect of Salviae Miltiorrhizae Radix et Rhizoma Polyphenols Acid Salt Combined with Adenosine Cyclophosphate Meglumine on Hemorheology, hs-CRP and NT-proBNP of Post-PCI Patients With Coronary Heart Disease[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(17): 152-155. DOI: 10.13422/j.cnki.syfjx.2015170152.
Objective: To observe the effect of Salviae Miltiorrhizae Radix et Rhizoma polyphenols acid salt combined with adenosine cyclophosphate meglumine on symptoms
cardiac functions and hemorrheology of patients with coronary heart disease after the percutaneous coronary Intervention (PCI). Method: Totally seventy-eight post-PCI cases of coronary heart disease were randomly divided into 2 groups:the control group (routine postoperative therapy
33 cases) and the treatment group (conventional therapy combined with intravenous dropping of 200 mg Salviae Miltiorrhizae Radix et Rhizoma phenolic acid salt and 120 mg adenosine cyclophosphate meglumine
qd
45 cases). The treatment time lasted from 24 h before the surgery to 2 weeks after the surgery. The clinical efficacy and changes in heart function and hemorrheology were observed. Result: The symptoms were relieved. After the treatment
the two groups showed statistical significance in whole blood high shear viscosity
low shear viscosity
plasma viscosity
D-dimer
hypersensitive C-reactive protein (hs-CRP) and pro-brain natriuretic peptide (NT-proBNP) compared with values before the treatment (P<0.05)
and the treatment group is more obvious
with statistical significance in differences (P<0.05). Conclusion: Salviae Miltiorrhizae Radix et Rhizoma polyphenols acid salt combined with adenosine cyclophosphate meglumine can improve hemorrheology
clinical symptoms and cardiac function among of post-PCI patients with coronary heart disease.