Objective: To study individual biomass of vegetative organs and alkaloids content in rhizome of Coptidis Rhizoma under different growth condition

and provide basic research data of optimal conditions for this herb in Emei county. Method: The weighing method and RP-HPLC was applied to determined biomass and compare contents of alkaloids in Coptidis Rhizoma under different altitude

shading way and cultivation density from Emei GAP base. Result: At an altitude of 1 200-1 800 m in Emei county

individual biomass of Coptidis Rhizoma had no significant difference

and contents of seven kinds of alkaloids conformed to requirement of the 2010 edition of Chinese Pharmacopoeia.Compared with traditional covering means

one and two layer shading net was no significant difference

but the new technology was saving labor and materials

protecting the forest resources.Production increased 32% per hectare with planting spacing of 10 cm×10 cm by comparing with 12 cm×12 cm. Conclusion: This study indicates that proper plant method

which is in altitude of 1 200-1 800 m

with monolayer net and planting spacing of 10 cm×10 cm

should be taken to improve quality and output of Coptidis Rhizoma.This method is proved to be practical for quality control of samples from GAP base of Coptidis Rhizoma.