炮制对决明子中萘并吡喃酮苷及蒽醌苷元类成分含量的影响

唐力英; 徐义龙; 周喜丹; 周国洪; 寇真真; 王婷; 王祝举

doi:10.13422/j.cnki.syfjx.2015180069

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炮制对决明子中萘并吡喃酮苷及蒽醌苷元类成分含量的影响

化学与分析 | 更新时间：2024-01-04

- 炮制对决明子中萘并吡喃酮苷及蒽醌苷元类成分含量的影响
- Effect of Processing on Naphthopyrone Glycosides and Anthraquinone Aglycone in Semen Cassiae
- 中国实验方剂学杂志 2015年21卷第18期页码：69-72
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家自然科学基金面上项目(81173552)
- DOI：10.13422/j.cnki.syfjx.2015180069
  中图分类号： R284.1
- 纸质出版日期：2015
- 稿件说明：
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唐力英, 徐义龙, 周喜丹, 等. 炮制对决明子中萘并吡喃酮苷及蒽醌苷元类成分含量的影响[J]. 中国实验方剂学杂志, 2015,21(18):69-72.

TANG Li-ying, XU Yi-long, ZHOU Xi-dan, et al. Effect of Processing on Naphthopyrone Glycosides and Anthraquinone Aglycone in Semen Cassiae[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(18): 69-72.
唐力英, 徐义龙, 周喜丹, 等. 炮制对决明子中萘并吡喃酮苷及蒽醌苷元类成分含量的影响[J]. 中国实验方剂学杂志, 2015,21(18):69-72. DOI： 10.13422/j.cnki.syfjx.2015180069.

TANG Li-ying, XU Yi-long, ZHOU Xi-dan, et al. Effect of Processing on Naphthopyrone Glycosides and Anthraquinone Aglycone in Semen Cassiae[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(18): 69-72. DOI： 10.13422/j.cnki.syfjx.2015180069.

摘要

目的: 比较炮制对决明子中主要活性成分萘并吡喃酮苷和蒽醌苷元类成分的影响。方法: 采用高效液相色谱法检测决明子中3个萘并吡喃酮苷和3个蒽醌苷元的含量

并比较其炮制前后的含量变化。结果: 炮制后决明子中3种萘并吡喃酮苷类成分含量均有明显下降

其中红镰霉素龙胆二糖苷下降约21%

决明子苷下降约60%

决明子苷C下降约87%;3种蒽醌苷元变化情况为

橙黄决明素和甲基钝叶决明素的含量变化没有显著性差异

钝叶素的含量升高48%。结论: 炮制对决明子主要活性成分萘并吡喃酮苷和蒽醌苷元类的含量均会产生显著影响

其中炮制后萘并吡喃酮苷类成分整体下降

蒽醌苷元类成分有部分含量升高。

Abstract

Objective: To compare the effect of processing on naphthopyrone glycosides and anthraquinone aglycones in Semen Cassiae. Method: The high-performance liquid chromatographic method was used to determine the content of three naphthopyrone glycosides and three anthraquinone aglycones in Semen Cassiae and compare the changes in the content before and after processing. Result: The content of three naphthopyrone glycosides significantly decreased after processing. Specifically

rubrofusaringentiobioside dropped about 21%

cassiaside decreased by 60%

cassiaside C decreased by 87%. As for the changes in the content of the three anthraquinones

there was no significant difference between aurantio-obtusin and chryso-obtusin

but obtusifolin increased by 48%. Conclusion: Processing has a significant effect on the content of naphthopyrone glycosides and anthraquinone aglycones in Semen Cassiae. Specifically

naphthopyrone glycosides in Semen Cassiae decreased integrally

whole anthraquinone aglycones increased partially after processing.

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