Objective: To investigate the clinical efficacy of Jinshiyin prescription combined with extracorporeal shock wave lithotripsy (ESWL) in treating urolithiasis and its effect on serum lipids in patients with urolithiasis. Method: Totally one hundred and twenty cases of eligible urolithiasis patients were divided into two groups according to therapeutic scheme

the control group (n=60) and the observation group(n=60). The control group was treated with ESWL

and the observation group was treated with Jinshiyin prescription combined with ESWL. The follow-up visit lasted for one year. The curative efficacy

recurrence rate

urine culture result and changes in serum lipid between both groups were observed and compared. Result: The observation group showed a therapeutic efficiency ratio of 96.7%

which was significantly higher than that of 83.3% in the control group (P<0.05). After the one-year follow-up visit

the recurrence rate in the observation group was 1.7%

which was statistically lower than that of 13.0% in the control group (P<0.05). Compared with the control group

the observation group showed reductions in the proportion of positive urine culture results

total cholesterol (TC)

triglyceride (TG) and low-density lipoprotein (LDL-C) and increase in high-density lipoprotein (HDL-C) after the treatment

with statistical significance in differences (all P<0.05). Conclusion: Jinshiyin prescription combined with ESWL in treating urolithiasis is an effective therapeutic scheme

which can increase the therapeutic efficacy

decrease the recurrence rate and urinary infection and effectively regulate serum lipid.