Objective: To discuss the composition rule of clinical prescriptions for peptic ulcer. Method: Totally 99 Chinese medicine literatures for treating peptic ulcer were retrieved by CNKI database. Their clinical prescription composition data was mined by Traditional Chinese Medicine Inheritance Support System

the methods included drug frequency statistics and association rule analysis on drug combination. Result: Totally 29 herbs were used over 10 times in the 147 traditional Chinese medicine herbs in the 99 prescriptions;40 medicine pairs were got in the condition of 20 support degree;8 medicine pairs were got when degree of confidence exceeded or equaled to 0.9. Conclusion: The most commonly used drugs for treating peptic ulcer in clinic were those strengthening the spleen and replenishing Qi

soothing the liver and regulating Qi

eliminating dampness and phlegm

and clearing fire medicines;peony licorice decoction

wujisan

and sinisan are common combined prescriptions for treating peptic ulcer.