MA Jin, YU Neng-wei, WU Hang-hai, et al. Effect of Danhong Injection on Nerve Function and Hemorheology for Patients with Acute Ischemic Stroke[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(20): 204-207.
MA Jin, YU Neng-wei, WU Hang-hai, et al. Effect of Danhong Injection on Nerve Function and Hemorheology for Patients with Acute Ischemic Stroke[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(20): 204-207. DOI: 10.13422/j.cnki.syfjx.2015200204.
Objective: To probe into clinical application value and significance of Danhong injection for patients with acute ischemic stroke. Method: Totally 90 acute ischemic stroke patients treated in our hospital From June 2013 to June 2014 were selected. The patients were divided into study group and control group randomly. There were 45 cases in each group. The patients in control group were treated with conventional regimen
including lowering the intracranial pressure
anti-platelet aggregation and neuroprotective agents. The patients in study group were treated with Danhong injection in addition to the therapies in control group. The neurological recovery
changes of hemorheology and improvements in activities of daily living of the patients in two groups were compared and analyzed. Result: Compared with control group
the patients in study group showed significant increases in the ratio of neurological improvement at 46.67%(21/45) and total efficiency at 91.11%(41/45)
the differences were significant statistically (P<0.05). Compared with control group
after treatment
the patients in study group showed significant decreases in the plasma viscosity at (1.39±0.21) mPa·s
whole blood viscosity at high shear value at (5.91±0.12) mPa·s
whole blood viscosity at low shear value at (7.18±1.34) mPa·s
hematocrit at (40.23±4.15)%
platelet adhesion rate at (26.73±5.24)%
the differences were significant statistically (P<0.05). Compared with control group
after treatment
the patients in study group showed significant increases in BI scores at (74.61±7.82) points and FMA scores at (54.88±5.36) scores
the differences were significant statistically (P<0.05). Conclusion: Danhong injection has extremely important clinical significance in recovering nerve function
improving hemorheology and enhancing daily living for patients with acute ischemic stroke. It was worth further applying and promoting.