Analyzing Professor Yin Changjian's Composition Principles of Prescriptions for Treating Cirrhosis by Traditional Chinese Medicine Inheritance Support System
YAN Xiao-yan, AN Yong, SHAO Jian-zhen. Analyzing Professor Yin Changjian's Composition Principles of Prescriptions for Treating Cirrhosis by Traditional Chinese Medicine Inheritance Support System[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(20): 225-230.
YAN Xiao-yan, AN Yong, SHAO Jian-zhen. Analyzing Professor Yin Changjian's Composition Principles of Prescriptions for Treating Cirrhosis by Traditional Chinese Medicine Inheritance Support System[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(20): 225-230. DOI: 10.13422/j.cnki.syfjx.2015200225.
Objective: This research uses traditional Chinese medicine(TCM) inheritance support system to analyze the composing principles of the prescriptions given by Professor Yin Changjian for treating cirrhosis. Method: We collected the prescription used for cirrhosis cases
then created the related database to store the related information. We further utilized the TCM inheritance support system to analyze the composing principles. By using principle analysis
we revised mutual information
complex system entropy cluster and unsupervised hierarchical clustering to analyze composing principle. Result: We found 435 cases of prescriptions related to Cirrhosis. The frequency of each herb appeared in the database was calculated
and the most used 21 herbs including Amomi Fractus Rotundus
Galli Gigerii Endothelium Corneum
etc. The core combination is highly related to correlation between Amomi Fractus Rotundus and Amomi Fractus Rotundus or Polygoni Orientalis Fructus. Seven new prescriptions for different Cirrhosis stage are discovered. Conclusion: The approach used in this work
utilizing data mining methods(text mining and association relationship) based on TCM inheritance support system
clearly shows the composition principle of prescription for treating cirrhosis used by Professor Yin Changjian:the basical therapies are invigorating the spleen for eliminating dampness
invigorating the circulation of blood and removing dampness through diuresis
and resloving hard lump. Making a point of protecting stomach-Qi.Invigorating the spleen for resloving hard lump.Prescribing the herbs on the basis of diffent cirrhosis stage.