Objective: To optimize and standardize processing technology of processed Aconitum carmichaelii in Lingnan for improving production efficiency and quality of this herb. Method: Taking contents of diester-type alkaloids and mono-ester aconitum alkaloids as index

based on single factor tests

orthogonal test was adopted to investigate effects of soaking time

steaming time and frying temperature on processing technology of processed A. carmichaelii. Result: The best processing technology was as follows:soaked 5 d with 8% ginger juice

steamed 1.5 h with high pressure

frying temperature at 210-230 ℃ with sand.Contents of diester-type alkaloids and mono-ester aconitum alkaloids were 0.031 1

0.120 5 mg·g-1

respectively. Conclusion: This optimized processing technology is sable and feasible.It will be benefit for providing foundation for large production of processed A. carmichaelii with improving product quality and production efficiency.