Objective: To analyze the rules of Ye Tian-shi's prescriptions for treating stomachache in Ye Tian-shi's Medical Records by using traditional Chinese medicine inheritance support system (TCMISS). Method: The prescriptions for treating stomachache in YE Tian-shi's Medical Records were collected and then entered into TCMISS. The medication rules were analyzed by using data mining methods

including revised mutual information

complex system entropy cluster and unsupervised hierarchical clustering. Result: ① Based on the analysis of 105 prescriptions

20 herbs were used for more than 10 times in the database. ② 19 herb pairs were used for 11 times

when the support degree was set to 11.Moreover

when the confidence was set to 0.6

the association rules for the herbs in the prescriptions were obtained. ③ 14 pairs of new core herbal combinations and 7 new prescriptions were obtained by using entropy cluster and hierarchical clustering methods. ④ The similarity of 20 prescriptions including Jinlingzi power was searched by matching prescriptions. Conclusion: The rules of Ye Tian-shi's prescriptions for treating stomachache were summarized through TCMISS

which will provide the data support for in-depth studies on Ye's prescriptions.