Objective: To realize quality control of water extracting process

near-infrared (NIR) spectroscopy was used to establish a rapid quantitative analysis model for the content of gastrodin and total solid content in the second water extracting process of Tianshu capsules

which could timely reflect its state. Method: Samples of the second water extracting process of Tianshu capsules were collected

after rejection of abnormal samples

pretreatment of spectra and choice of corresponding wave band

multivariate calibration models were respectively established by partial least squares (PLS) algorithm between spectra and the content of gastrodin or total solid content.Samples in the concentrating process

which did not participate in modeling were used to test performance of models. Result: Correlation coefficients of the content of gastrodin and total solid content were 0.9680 and 0.9772;predicted coefficients of them were 0.9659 and 0.9786

root mean square error of calibration (RMSEC) were 4.686 and 0.053

root mean square error of prediction (RMSEP) were 3.698 and 0.034

and the relative standard errors of predictions (RSEP) were 4.85% and 3.07%

respectively. Conclusion: The method mentioned above is proved to be convenient

rapid

accurate and applicable for fast analysis and monitoring of active components in the second water extraction process of Tianshu capsules.