Objective: To probe into the clinical application value of Reduning injection combined with salmeterol and fluticasone propionate inhalation powder for patients with bronchial asthma. Method: From January 2013 to June 2014

110 patients with bronchial asthma were selected in our hospital. The patients were divided into treatment group (n=55) and control group (n=55) with random number table. The patients with bronchial asthma in control group were treated salmeterol and fluticasone propionate inhalation powder

1 suction/time

2 times/d

14 d/treatment. The patients with bronchial asthma in treatment group were treated combined with Redunning injection therapy based on control group

20 mL/second

1/d

14 d/treatment. The clinical treatment

changes of pulmonary function

expression of inflammatory cytokines

cell-mediated immunity factor of the patients in two groups were compared and analyzed. Result: Compared with control group

the patients in treatment group

efficiency ratio was 47.27% (26/55) and total efficiency ratio was 92.73% (51/55)

there were increased significantly

the differences were significant statistically (P<0.05). Compared with before treatment

the patients in two groups after treatment

the indexes of lung function

included forced vital capacity (FVC)

the first second forced expiratory volume (FEV1) and forced expiratory flow rate (FEF) were increased significantly

the differences were significant statistically (P<0.05). Compared with control group

the patients in treatment group after treatment

the indexes of lung function

included FVC was (3.01±0.17) L

FEV1 was (2.86±0.51) L and PEF (4.96±1.10) L·s-1

there were increased significantly

the differences were significant statistically (P<0.05). Compared with before treatment

the patients in two groups after treatment

the levels of inflammatory cytokines interferon-γ(IFN-γ) were increased significantly

and the levels of interleukin-4(IL-4)were decreased significantly

the differences were significant statistically (P<0.05). Compared with control group

the patients in treatment group after treatment

the level of inflammatory cytokines IFN-γ was (21.69±3.14) ng·L-1

there was increased significantly

and the level of IL-4 was (8.97±1.67) ng·L-1

there was decreased significantly

the differences were significant statistically (P<0.05). Conclusion: Reduning injection combined with salmeterol and fluticasone propionate powder has very important significance for improving the clinical effect

lung function and inflammatory cytokines expression of patients with bronchial asthma.