Objective: To evaluate the effectiveness of Qingyi decoction in the treatment of severe acute panereatitis in a systematic review. Method: The inclusion and exclusion criteria and retrieval strategies were made using Meta-analysis methods

with computer retrieval of CNKI (1979-2014)

Wanfang Data Knowledge Service Platform (1990-2014)

Chinese Biomedical Database (1978-2014)

pubmed (1966-2014) and other Chinese and English databases.The quality of the literatures was assessed according to Cochrane review criteria. Result: The 19 studies were included. Compared with control group

the adjunctive therapy with Qingyi decoction group had significant differences in the time of first defecation[WMD=-2.098

95%CI(-2.739

-1.456)

P<0.01)]

the time of stomach ache relief[WMD=-3.008

95%CI(-3.689

-2.326)

P<0.01]

hospital stay (days)[WMD=-7.633

95%CI(-8.449

-6.756)

P<0.01]

case fatality rate[OR=2.719

95%CI (1.717

4.306)

P<0.01]. Conclusion: The adjunctive therapy with Qingyi decoction in severe acute pancreatitis can significantly decrease the case fatality rate

shorten the first time of defecation

stomachache relief time and hospital stay.