Influence of Xiangsha Bazhen Decoction Combined with Enteral Nutrition on Postoperative Immune Functions of Patients with Gastrointestinal Tumor Surgery
LI Sui-bang, XU Yan-lin. Influence of Xiangsha Bazhen Decoction Combined with Enteral Nutrition on Postoperative Immune Functions of Patients with Gastrointestinal Tumor Surgery[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(24): 169-172.
LI Sui-bang, XU Yan-lin. Influence of Xiangsha Bazhen Decoction Combined with Enteral Nutrition on Postoperative Immune Functions of Patients with Gastrointestinal Tumor Surgery[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(24): 169-172. DOI: 10.13422/j.cnki.syfjx.2015240169.
Objective: To observe the influence of Xiangsha Bazhen decoction combined with enteral nutrition on nutritional status
quality of life and immune functions in patients with gastrointestinal tumor surgery. Method: One hundred and thirty patients with gastrointestinal tumors were randomly divided into control group and observation group. Patients in control group received enteral nutrition. Based on the treatment of control group
patients in observation group received additional Xiangsha Bazhen decoction. Course of treatment was 14 days for both groups. Levels of serum immune globulin IgG
IgA and IgM
T-lymphocyte subpopulations in blood(CD3+
CD4+ and CD4+/CD8+) and natural killer cell(NK) were measured. Before and after treatment
scores of SF-36 health survey scales were graded
and levels of serum albumin(Alb)
prealbumin(PA)
hemoglobin(Hb) and transferrin(TRF) were also detected. Result: Compared with the data before treatment
levels of CD3+
CD4+
CD4+/CD8+ and NK in observation group were increased after treatment(P<0.01)
higher than those in control group(P<0.01). After treatment
levels of IgG
IgA and IgM in observation group were increased(P<0.01)
and higher than those in control group(P<0.05
P<0.01). Levels of Alb and Hb after treatment were higher than those in control group
but there was no statistically significant difference in PA and TRF between two groups. Scores of pars trunci function(PF)
social function(SF)
role emotional(RE)
vitality(VT)
mental health(MH) and general health(GH) after treatment were higher than those in control group(P<0.01). Conclusion: Xiangsha Bazhen decoction combined with enteral nutrition can ameliorate nutritional status and immune function
improve quality of life and promote the recovery of disease in the treatment of patients after gastrointestinal tumors.