Objective: To systematically evaluate the safety and efficacy of Gegen Qinlian Tang in treating infantile rotavirus enteritis. Method: We searched Cochrane Library

Pubmed

Embase

CNKI

CBM

VIP and Wanfang Data through computer for data as at June 13

2015.All of randomized controlled trials(RCTs) of Gegen Qinlian Tang in treating infantile rotavirus enteritis were searched

and research literatures included in the RCTs were also traced. Two researchers independently conducted the strict quality evaluation and data extraction for the included studies and made a Meta-analysis by using RevMan 5.3 software. Result: Totally 10 RCTs involving 1092 patients were included into the study. The Meta-analysis results showed that compared with the control group

Gegen Qinlian Tang can significantly improve the clinical effective rate[OR=4.27

95%CI(2.76

6.62)

P<0.00001]

and showed the combined test analysis result of Z=6.49

with statistically significant differencesin both groups. Conclusion: Gegen Qinlian Tang in treating infantile rotavirus enteritis can effectively improve the clinical effective rate. However

due to the low methodology and quality and small sample size of included RCTs in this study

more restrict high-quality multicenter RTCs are required to further verify the efficacy and safety of Gegen Qinlian Tang in treating infantile rotavirus enteritis.