Objective: To compare contents of total saponins and platycodin-D in Platycodonis Radix from different origin. Method: Contents of total saponins and platycodin-D in 36 batches of Platycodonis Radix samples from different origin were determined by methods in the 2005 edition and the 2010 edition of Chinese Pharmacopoeia

respectively. Result: Content distribution range of total saponins in 10 batches of samples from Chifeng was 5.02%-9.20%

content of platycodin-D was 0.1%-0.175%

both of content distribution range was relative narrow

which meant their quality was more stable than others.Contents of total saponins and platycodin-D from other districts had a large scale distribution

which meant quality of Platycodonis Radix between Chifeng and other districts was very different. Conclusion: Chifeng obtains a continental climate

and could be developed into an important production base to make quality of Platycodonis Radix consistently.