Objective: Angelicae Sinensis Radix(ASR) is commonly used in compatibility with many other herbs

reflecting good synergism and restriction functions

thus forming a series of herb pairs. This study is aimed to investigate the potential rules of herb pairs containing ASR. Method: We retrieved 16529 formulaes which contain ASR from the 'Dictionary of Traditional Chinese Medicine Formulae'

then built the database according to the frequency statistical method

and analyzed the compatibility proportion

corresponding indicated diseases and departments. Result: There were 170 herbs(compatibility frequency>200 with ASR) and even 22 herbs(compatibility frequency>1500). Further analysis of these 22 ASR series prescriptions showed that their compatibility proportion 1:1 was the most common

followed by 1:2 and 3:2.In addition

they were most frequently used for the treatment of the diseases in internal medicine and gynecology. Conclusion: In this paper we first formulate the data of series of herb pairs containing ASR in traditional Chinese medicine clinical application and find some regular characteristics of herb pairs containing ASR in clinical prescription

which provide the guidance and reference for the modern research and application of relative herb pairs and formulae.