XU Hua-ping, JIN Guo-qin. Review of Research on Bushen Yiqi Prescription in Retarding Mitochondrial Function Degradation of Skeletal Muscle[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 224-228.
XU Hua-ping, JIN Guo-qin. Review of Research on Bushen Yiqi Prescription in Retarding Mitochondrial Function Degradation of Skeletal Muscle[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 224-228. DOI: 10.13422/j.cnki.syfjx.2016010224.
This article uses literature summary method to analyze relationship between mitochondrial structure
membrane permeability
oxidative damage
respiratory function
enzyme activity
mitochondria biosynthesis and skeletal muscle aging
it explores influence of Bushen Yiqi prescription on mitochondria structure and function of ageing skeletal muscle
in order to provide theory basis for taking appropriate traditional Chinese medicine to retard skeletal muscle ageing.It is found that
as body gradually aging
mitochondrial structure in skeletal muscle became disorder
permeability of mitochondrial membrane changed
mitochondria suffers oxidative damaged
respiratory function
enzyme activity and mitochondria biosynthesis decreased
Bushen Yiqi prescription can retard skeletal muscle aging through improving mitochondrial structure and function of aging skeletal muscle
but its deep mechanism of action was not clear.How to combine modern experimental technology
under guidance of theory system of traditional Chinese medicine
multi-angle and multi-level to ascertain mechanism and structure-activity relationship of Bushen Yiqi prescription in retarding skeletal muscle aging is the key issue to be solved in process of developing this kind of herbs and formulae.