ZHANG Mei, GONG Xiao-meng, XIONG Rui, et al. Comparative Study on Pharmacodynamics of Pingwei San with Different Raw Material[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(2): 17-20.
ZHANG Mei, GONG Xiao-meng, XIONG Rui, et al. Comparative Study on Pharmacodynamics of Pingwei San with Different Raw Material[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(2): 17-20. DOI: 10.13422/j.cnki.syfjx.2016020017.
Objective:Based on copy corresponding pathologic model
to discuss rationality of processing by comparing pharmacodynamics of Pingwei San. Method:Rats were divided into seven groups randomly
such as the normal group
the model group
the positive group
Pingwei San group
Pingwei San with processed Glycyrrhizae Radix et Rhizoma group
Pingweisan with processed Atractylodis Rhizoma group and Pingwei San with processed products group.In addition to the normal group
models caused by improper dieting
excessive external dampness and emotional discomfort with the spleen and stomach being stranded by dampness.Propulsive rate of the small intestine
gastric residual rate and swimming exhaustion time were taken as evaluation indexes for treatment of Pingwei San. Result:Compared with the normal group
gastric residual rate
propulsive rate of the small intestine and anti-fatigue capability of the model group decreased significantly
which manifested the model was successful.Compared with the model group
each treatment group had a significant improvement effect
while the positive group and Pingwei San with processed products group had the greatest effect. Conclusion:After Glycyrrhizae Radix et Rhizoma and Atractylodis Rhizoma in Pingwei San being processed
this prescription is preferable for improving dampness obstructing spleen-stomach syndrome.