To sort out and analyze the literature on the damage mechanism of angiotensin Ⅱ to glomerular endothelial cells. Angiotensin Ⅱ

glomerular endothelial cells

endothelial cell injury were used as the keywords to search for the relevant literature on internal and abroad studies of glomerular endothelial cell damage mechanism in recent 10 years

and then the analysis was conducted. The results showed that angiotensin Ⅱcould cause glomerular endothelial cell injury through activating inflammatory reaction and oxidative stress

inducing apoptosis

injurying structure of glomerular endothelial cells and endocrine functions

as well as changing the dynamics of the renal blood flow and other ways. This study has great significance to further clarify the injury mechanism of angiotensin Ⅱto glomerular endothelial cells and find effective prevention and treatment methods.