XU Jing-li, LI Zhi-cheng, LIANG Zheng-rong, et al. Meta-analysis on Clinical Efficacy and Safety of Xiyanping Combined with Montmorillonite Power in Treatment of Infantile Diarrhea[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(3): 211-216.
XU Jing-li, LI Zhi-cheng, LIANG Zheng-rong, et al. Meta-analysis on Clinical Efficacy and Safety of Xiyanping Combined with Montmorillonite Power in Treatment of Infantile Diarrhea[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(3): 211-216. DOI: 10.13422/j.cnki.syfjx.2016030211.
Objective: To evaluate the efficacy and safety of Xiyanping combined with montmorillonite power in the treatment of infantile diarrhea. Method: literature were retrieved from Pubmed
Embase
Cochrane library
CNKI
CBM
Wanfang Data and VIP to select randomized clinical trials on Xiyanping combined with montmorillonite power for the treatment of infantile diarrhea. Rigorous quality evaluation and data extraction were done independently by two researchers
and treatment
RevMan 5.3 software was used for Meta-analysis. Result: 17 RCTs were eventually included
with a total of 1841 cases of children. Meta-analysis showed that:Xiyanping combined with montmorillonite power in the treatment of infantile diarrhea was statistically significant when compared with the control group intotal efficiency
the time of diarrhoea stop and recovery time of abnormal stool (P<0.05)
but there was no statistically significant difference in time of body fever relieving between the two groups. Conclusion: Xiyanping combined with montmorillonite power has a certain effect and high safety in the treatment of infantile diarrhea
but with the poor quality of the existing studies
we need to design more rigorous and high quality multicenter