Objective: To systematically review the efficacy of Gegensu injection combined with western medicine for curing Heart failure. Method: Such databases as PubMed

CENTRAL

CNKI

VIP

EMbase

Wanfang and CBM were electronically searched to collect the randomized controlled trials. The document screening and quality evaluation were conducted to extractvalid data for a Meta-analysis. Result: Totally 16 RCTs involving 1 291 cases were included. The results of Meta-analysis showed that compared with the pure western medicine treatment

the combination of Gegensu injection and western medicine were superior in clinical comprehensive effect [OR=3.95

95%CI(2.84

5.49)]

left ventricular ejection fraction [MD=8.43

95%CI(3.41

13.45)]

stroke volume [MD=4.98

95%CI(3.20

6.75)]

cardiac output [MD=0.57

95%CI(0.19

0.94)]

cardiac index [MD=0.77

95%CI(0.33

1.20)] and reduction of heart rate [MD=9.71

95%CI(6.52

12.89)]

with significant statistical differences (P<0.05). Conclusion: Compared with the pure western medicine treatment

the combination of Gegensu injection and western medicine has a higher clinical efficacy in the treatment of heart failure.