Objective: Through the content determination of chlorogenic acid

mignonette glycosides

total phenolic acid

and total flavonoid in flos lonicerae from 14 different regions

to find out the correlation between the four components

and provide a reference for reasonable assessment of the quality of Loniceroe Japonicae Flos. Method: HPLC and UV method were used to determine the content of chlorogenic acid

mignonette glycosides

total phenolic acid and total flavonoid in Loniceroe Japonicae Flos

and correlation analysis method was used to measure their relationships. Result: With the content of four components as the comprehensive indicators

Loniceroe Japonicae Flos from Linyi in Shandong had the highest content in chlorogenic acid

mignonette glycosides

total phenolic acid

and total flavonoid. Through correlation evaluation

chlorogenic acid and total phenolic acid in Loniceroe Japonicae Flos were highly correlated;mignonette glycosides and total flavonoid were moderately correlated;chlorogenic acid and mignonette glycosides were moderately co-related;total phenolic acid and flavonoids were moderately correlated. Conclusion: The evaluation of index components and related analysis of Loniceroe Japonicae Flos from 14 different origins provide experimental data for quality evaluation and rational utilization of Loniceroe Japonicae Flos.