Clinical Observation of Maxin Shigan Tang Combined with Tingli Dazao Xiefei Tang as Modified Auxiliary Therapy for Community Acquired Pneumonia in Middle-aged and Old Patients
TAN Ya-yun, LIANG Dong. Clinical Observation of Maxin Shigan Tang Combined with Tingli Dazao Xiefei Tang as Modified Auxiliary Therapy for Community Acquired Pneumonia in Middle-aged and Old Patients[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(5): 202-205.
TAN Ya-yun, LIANG Dong. Clinical Observation of Maxin Shigan Tang Combined with Tingli Dazao Xiefei Tang as Modified Auxiliary Therapy for Community Acquired Pneumonia in Middle-aged and Old Patients[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(5): 202-205. DOI: 10.13422/j.cnki.syfjx.2016050202.
Objective: To observe the clinical efficacy of Maxin Shigan Tang combined with Tingli Dazao Xiefei Tang as modified auxiliary therapy for community acquired pneumonia (CAP) in middle-aged and old patients as well as its effect on C-reactive protein (CRP)
erythrocyte sedimentation rate (ESR) and procalcitonin (PCT). Method: One hundred and six cases patients with CAP were divided into control group (52 cases) and experimental group (54 cases) by random number table. Patients in control group received cefoperazone sodium and sulbactam sodium for intravenous infusion
3 g
2 times/day and azithromycin injection for intravenous infusion
0.5 g
1 time/day
with a treatment course of 14 days in total. Based on the treatment of control group
patients in experimental group added Maxin Shigan Tang combined with Tingli Dazao Xiefei Tang
1 dose/day
with a treatment course of 14 days. Before and after treatment
scores of main symptoms and signs were recorded;fevers
cough
expectoration
lung rale
lung slices
the blood and average stay were recorded. Before and after treatment
levels of CRP
ESR and PCT were detected. Result: In Ridit analysis
clinical effect in experimental group was superior to that in control group (P<0.05). After treatment
scores of the main symptoms and sings (cough
expectoration
sputum
wheeze
breathe hard
flustered and exasperated
lags in response
moist rales
excessive phlegm and bronchophony) were lower than those in control group (P<0.01). After treatment
time of fevers
cough
lung rale
recovery time in lung slices and blood examination as well as the average stay in experimental group were shorter than those in control group (P<0.05
P<0.01). Levels of CRP
ESR and PCT were also lower than those in control group after treatment (P<0.05
P<0.01). Conclusion: Maxin Shigan Tang combined with Tingli Dazao Xiefei Tang can relieve symptoms and signs
shorten courses
reduce levels of CRP
ESR and PCT
and improve clinical effect for the treatment of community acquired pneumonia (CAP) in middle-aged and old patients.