Objective: To investigate effect of different medicinal parts and preparation processes of Bupleurum chinense on quality of Chaihu injection. Method: Part on the ground

the underground part and the whole grass of B. chinense were extracted by distillation

distillation with salt

distillation with acid

distillation acid and salt

extract were detected and analyzed by the legal quality standard of WS3-B-3297-98-2011. Result: Different parts of B. chinense had little effect on characteristic spectrum determination results

but proportion between different chromatographic peaks in fingerprint had obvious difference;effect of different preparation processes of fingerprint was very obvious;other test items conformed to the legal standard requirements. Conclusion: Samples prepared by the original process do not detect furfural

samples of non-original process contain furfural.Different medicinal parts have small impact on quality of Chaihu injection.The current legal quality standard can not effectively control product quality

in order to ensure product quality

quality standard of Chaihu injection must revise.